Each year, influenza epidemics cause up to 5 million cases of severe illness and as many as 500,000 deaths, according to the World Health Organization.  The elderly, the very young, and those with chronic conditions are at the highest risk for life-threatening complications. Vaccines against influenza have been available for more than 60 years and can help prevent illness or reduce the severity of the disease and the incidence of complications.

Featured Articles

No High-dose trivalent influenza vaccine compared to standard dose vaccine in elderly adults: Safety, immunogenicity and relative efficacy during the 2009–2010 season
Carlos A. DiazGranados, Andrew J. Dunning, Emilia Jordanov, et al

High-dose trivalent influenza vaccine was developed to improve antibody responses to influenza vaccine in the elderly and hence potentially impact...

No Increasing childhood influenza vaccination: A cluster randomized trial
Mary Patricia Nowalk, Chyongchiou Jeng Lin, Kristin Hannibal, et al

Since the 2008 inception of universal childhood influenza vaccination, national rates have risen more dramatically among younger children than...

Yes Predictors of the timing of vaccination uptake: The 2009 influenza pandemic (H1N1) in Montreal
Luc de Montigny, Katia Charland, Aman Verma, et al

In response to the 2009 H1N1 influenza pandemic, Canada undertook the largest vaccination campaign in its history.

No Seasonal influenza vaccination reminders for children with high-risk conditions: A registry-based randomized trial
Kevin J. Dombkowski, Laura B. Harrington, Shiming Dong, Sarah J. Clark

Children with chronic conditions have an increased risk of complications from influenza and have low influenza vaccination rates.

No Cochrane re-arranged: Support for policies to vaccinate elderly people against influenza
Walter E.P. Beyer, Janet McElhaney, Derek J. Smith, et al

The 2010 Cochrane review on efficacy, effectiveness and safety of influenza vaccination in the elderly by Jefferson et al. covering dozens of...

No A systematic review of mandatory influenza vaccination in healthcare personnel
Samantha I. Pitts, Nisa M. Maruthur, Kathryn R. Millar, et al

Influenza is a major cause of patient morbidity. Mandatory influenza vaccination of healthcare personnel (HCP) is increasingly common yet has...

No Evaluating a standardized measure of healthcare personnel influenza vaccination
Megan C. Lindley, Suchita A. Lorick, Anita Geevarughese, et al

Methods of measuring influenza vaccination of healthcare personnel (HCP) vary substantially, as do the groups of HCP that are included in any...

Yes The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young children
Christopher C. Blyth, Peter C. Richmond, Peter Jacoby, et al

Parental attitudes towards vaccination significantly influence vaccine uptake. The A(H1N1)pdm09 influenza pandemic was followed in 2010 by an...

No Conscious consideration of herd immunity in influenza vaccination decisions
Andrew M. Parker, Raffaele Vardavas, Christopher S. Marcum, Courtney A. Gidengil

Influenza vaccination decisions may be influenced by perceived risk reduction related to herd immunity.

No Influenza vaccination among persons with work-related asthma
Jacek M. Mazurek, Gretchen E. White, Jeanne E. Moorman, Eileen Storey

Seasonal influenza vaccination is recommended for all asthma patients. Persons with work-related asthma may have more severe disease than those...

No Influenza A (H1N1) 2009 monovalent vaccination among adults with asthma, U.S., 2010
Peng-jun Lu, David B. Callahan, Helen Ding, Gary L. Euler

The 2009 pandemic influenza A (H1N1) virus (2009 H1N1) was fırst identifıed in April 2009 and quickly spread around the world.

No Influenza vaccination coverage among adult survivors of pediatric cancer
Rohit P. Ojha, Tabatha N. Offutt-Powell, James G. Gurney

A large proportion of long-term survivors of childhood cancer have treatment-related adverse cardiac and pulmonary late-effects, with related...

No Influenza vaccination of Michigan children by provider type, 2010–2011
Joshua L. Clayton, Rachel C. Potter, Eden V. Wells, et al

Influenza vaccination for all children aged 6 months to 18 years has been recommended since 2008 to prevent flu-related morbidity and mortality....

No Vaxtracker: Active on-line surveillance for adverse events following inactivated influenza vaccine in children
Patrick Cashman, Sarah Moberley, Craig Dalton, et al

Vaxtracker is a web based survey for active post marketing surveillance of adverse events following immunization. It is designed to efficiently...

No 2009 Pandemic influenza A vaccination of pregnant women: King County, Washington State, 2009–2010
Meagan K. Kay, Kathryn G. Koelemay, Tao Sheng Kwan-Gett, et al

The objectives were to estimate 2009 pandemic influenza A (pH1N1) vaccination coverage among pregnant women and identify associated factors.